Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Upon entry into the target cell, the viral RNA genome is converted reverse transcribed into double-stranded DNA by a virally encoded enzyme, reverse transcriptase , that is transported along with the viral genome in the virus particle. The resulting viral DNA is then imported into the cell nucleus and integrated into the cellular DNA by a virally encoded enzyme, integrase , and host co-factors. Alternatively, the integrated viral DNA may be transcribed , producing new RNA genomes and viral proteins, using host cell resources, that are packaged and released from the cell as new virus particles that will begin the replication cycle anew. Two types of HIV have been characterized:
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Immigration regulation Each of these strategies has widely differing levels of efficacy, social acceptance, and acceptance in the medical and scientific communities. Over 60 countries impose some form of travel restriction, either for short- or long-term stays, for people infected with HIV. These persuasive messages have successfully increased people's knowledge about HIV. More importantly, information sent out through advertising and social marketing also proves to be effective in promoting more favorable attitudes and intentions toward future condom use, though they did not bring significant change in actual behaviors except those were targeting at specific behavioral skills.
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There is now a wealth of evidence on how, when and where HIV first began to cause illness in humans. You can find out more about the origins and history of HIV through our interactive timeline , where you can read, watch, listen and explore key events from the history of the epidemic. The researchers who discovered this connection concluded that it proved chimpanzees were the source of HIV-1, and that the virus had at some point crossed species from chimps to humans. They discovered that the chimps had hunted and eaten two smaller species of monkeys red-capped mangabeys and greater spot-nosed monkeys.
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